现代化学与应用

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Analytical Determination of Lisinopril Using UV Spectrophotometer and HPLC: An Overview

Safila Naveed

Present review article determine the analytical methods for the quantitative determinations of lisinopril (ACE Inhibitor) by UV spectrophotometery and High-Performance Liquid chromatography. Pharmaceutical analysis of lisinopril requires effective analytical procedures for QC quality control analysis in Pharmaceuticals dosage formulations and human serum. An extensive survey for determination of LSP compiled from the research articles published in various pharmaceutical and analytical chemistry Journals. This appraisal illustrate that majority of the HPLC methods reviewed are based on the quantitative analysis of drug in Active Pharmaceutical ingredients (API), formulations, biological fluids such as serum and plasma and they are appropriate for therapeutic monitoring of drug, for pharmacokinetic purpose.