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Citrus reticulate peel extracts a promising natural obesity therapy

Iman Kamel

The potential benefits of the water extract of Citrus reticulate peel were assessed on obesity and fat reduction in adolescent. Clinical trials were done on double-blind, placebo-controlled study, 40 obese adolescent subjects/each group randomized from both sex with age vary between 12 and 18 years old. Group A participants received an 800 mg of dry extract daily and group B received placebo. Both groups received three meals (2000 kcal/day) throughout the study. The primary outcome in group A was reduction in Body mass index (BMI), Body fat percentage (BF%) and in waist circumference (WC). Secondary outcomes were significant reduction in BMI, BF% and WC, as well as better lipid profile criteria. Statistically high significant reductions in BMI by 5.74 kg/m2 (P< 0.001), WC by 11.33 cm (P< 0.001), body fat by 4.24%(P= 0.006), total cholesterol (TC) by 35.56 mg/dl (P= 0.008) and triglyceride (TG) by 24.66 mg/dl (P< 0.001) were observed in the group A compared to the group B as study conclusion. Many of the beneficial effects in management of obesity attributed to the presence of polyphenols and flavonoids constituents of the extract