干细胞研究与治疗杂志

抽象的

Combined Cellular Therapy for Osteoarthritis and Osteonecrosis of the Hip: A Case Report with 2 Year Follow-up

Kevin F Darr and Katelyn M Daigle

Introduction: The use of autologous bone marrow aspirate, adipose tissue, and platelet-rich plasma has the potential to provide pain relief and improve function in individuals with orthopedic conditions. This case report reflects the results of an individual who was treated with cellular therapy for osteoarthritis and osteonecrosis of the hip. This provides some evidence that combined cellular medicine has the potential to halt the progression of osteoarthritis and osteonecrosis and delay or prevent the need for surgical intervention. Case presentation: The patient in this report is a 43 year old male who presented with osteoarthritis and osteonecrosis of the left hip. After failing conservative treatment, the patient was considering surgical intervention but instead elected to proceed with combined cell therapy. Conclusion: Two years after treatment the patient was able to return to activities of daily living and physical activity, including bike riding, after one treatment. An MRI revealed no further progression of osteoarthritis or osteonecrosis and no collapse of the femoral head. The patient was satisfied with treatment and reports very little to no pain at all. This report, combined with the array of knowledge within the field of orthobiologics, has the potential to alter standard treatment in orthopedics and reduce the necessity of surgical intervention.