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Evaluation of Periodontal and Hematological Findings in Diabetes Patients- A Case Control Study

Paavai Ilango, Ayswarya V Vummidi, Vasugi Suresh, Veejai Chandran, Vidhya S Bharathy, Yogesh G, Arulpari Mahalingam, Angel Rajamani and Vineela Katam Reddy

Background: Periodontal disease is a chronic inflammatory disease initiated by bacterial pathogens and modified by various risk factors. Various studies have elucidated the converse side of the relationship between systemic health and oral health proving the adverse effect of systemic health on periodontal disease and vice-versa. Amongst all, a strong correlation has been shown between periodontal disease and diabetes, revealing that periodontitis is a proven sixth complication for diabetes. There is an emerging evidence to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis and its inflammation affecting the glycemic control.
Method: The aim of this case-control study was to evaluate the periodontal and hematological manifestations in diabetic and non-diabetic patients. The sample size was estimated as n=264 with n=132 in each group. 2.5 ml of blood was withdrawn from each of the patient for hematolgical evaluation: HbA1c values, Hb%, RBC count, the differential count and total leukocyte count. Periodontal evaluations were assessed by probing pocket depth, clinical attachment level and Russell’s periodontal score.
Results: There was statistically significant (p=0.000) difference in the diabetic group than the control group with respect to smoking, alcohol consumption, Hb%, HbA1c levels, differential counts, total leukocyte count, probing pocket depth, clinical attachment level and Russell’s periodontal score. RBC count and gender revealed no significance.
Conclusion: There was an higher periodontal manifestations corresponding to the altered haematological findings in diabetic patients than non-diabetic patients with higher prevalence in smokers and alcohol consumers.