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Heterogeneity of Progenitor Cell Populations and their Therapeutic Implications

Elizabeth R Zielins, Anna Luan, Ruth Tevlin, Victor W Wong, Arash Momeni, Michael T Longaker and Derrick C Wan

Stem cell populations throughout the human body are known to be heterogenous, though the extent of their heterogeneity and how this can be harnessed to provide more effective tissue regeneration remains questionable. Herein we describe not only the existence of heterogenous progenitor populations in a variety of tissues, but also currently utilized means for isolation of them, and the particular promise held in the ability to isolate progenitor cell populations from adipose-derived stromal cells.