生物等效性和生物利用度杂志

抽象的

Risks of the Meiliang Bay Source of Drinking Water in Taihu Lake (MLBSDW- THL) on Environmental Health

Shifeng Yun, Xiaoyun Tian, Shupei Cheng, Yan Zhang, Libo Zhang, Li Chen, Lianqin Guo, Hongling Zhang, Fei He, Weixin Li and Yunzhong Shi

There was a cyanobacteria bloom occurred in the area of Meiliang Bay source of drinking water in Taihu Lake (MLB-SDW-THL) in 2007 when MLB-SDW-THL couldn’t be used to make a tap water for people drinking and washing. Three years later, whether MLB-SDW-THL had biochemical effects on the mouse serum was researched for predication of its risks on human and environmental health. The water samples of MLB-SDW-THL were taken at N31.53 and E120.21 in March of 2010 and kept at 4°C for the experiment. Measurement of 22 organic pollutants with DSQ II Single Quadruple GC/MS in selected ion monitoring (SIM) indicated that 11 of them were discovered in MLB- SDW-THL. Mice Mus musculus were fed with MLB-SDW-THL for 90d under standard conditions. The eighteen serum biochemical parameters, the clinical parameters used in China hospitals, were measured by Automatic Biochemical Analysis/RerLi 600 and the parameter data treated by One-Way ANOVA statistic approach. The results showed that among the measured eighteen serum biochemical parameters, six of the 18 parameter levels were decreased significantly (0.01