微生物与生化技术杂志

抽象的

Systematic Literature Review of Avian Influenza Virus Prevalence in Birds and Humans Globally from 1918 to 2018

Abduleziz Jemal Hamido , * Milion Shiferaw

Avian influenza viruses are now widely recognized as important threats to agricultural biosecurity and public health, and as the potential source for pandemic human influenza viruses. Human infections with avian influenza viruses have been reported from Asia (H5N1, H5N2, H9N2), Africa (H5N1, H10N7), Europe (H7N7, H7N3, H7N2), and North America (H7N3, H7N2, H11N9). Direct and indirect public health risks from avian influenza are not restricted to the highly pathogenic H5N1 “bird flu” virus, and include low pathogenic as well as high pathogenic strains of other avian influenza virus subtypes, e. g., H1N1, H7N2, H7N3, H7N7, and H9N2. Research has shown that the 1918 Spanish Flu pandemic was caused by an H1N1 influenza virus of avian origins, and during the past decade, fatal human disease and human-to-human transmission has been confirmed among persons infected with H5N1 and H7N7 avian influenza viruses. Our ability to accurately assess and map the potential economic and public health risks associated with avian influenza outbreaks is currently constrained by uncertainties regarding key aspects of the ecology and epidemiology of avian influenza viruses in birds and humans, and the mechanisms by which highly pathogenic avian influenza viruses are transmitted between and among wild birds, domestic poultry, mammals, and humans.