药物流行病学和药物安全性的进展

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Welcome to the Special Edition of Recent Advances in Pharmacokinetics and Pharmacodynamics

Richard L Slaughter

I am pleased to welcome you the Special Edition of Advances in Pharmacoepidemiology and Drug Safety that focuses on Recent Advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). I do hope that you find the manuscripts in this edition of interest. This edition provides a wide scope of related articles in the area of PK/ PD. Articles range from highly theoretical articles related to Bayesian forecasting to very practical articles that deal with very common issues in clinical practice such as vancomycin doing in morbid obese patients. Specifically, readers who have an interest in Bayesian pharmacokinetics and pharmacodynamics will appreciate the article by Dr. Verotta on covariate modeling PK/PD studies and that of Drs. van der Meerm and Neef on optimum sampling strategies. This latter paper argues that Maximum A Posterioiri Bayesian (MAPB) estimation be used for pharmacokinetic parameter estimation over multiple regression analysis in Bayesian forecasting studies.