Wang Lee
Phenomena like double layer overlap, high surface-to-volume ratios, surface charge, ion-current rectification, and entropic barriers can influence transport in and around nanofluidic structures because the length scales of these forces and the critical dimensions of the device are similar. As a result, ion, particle, and fluid transport in nanofluidic devices has received a lot of attention over the past two decades.1,2In order to study these phenomena and their effects on ion and fluid transport, advancements in micro- and nanofabrication techniques have made it possible to design a variety of well-defined nanofluidic geometries. This review focuses on recent advancements in nanofabrication techniques as well as studies of fundamental transport in nanofluidic devices.3,4 The integration of micro- and nanofluidic structures into lab-on-a-chip devices enables increased functionality that is useful for a variety of analytical applications.