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Analysis of the Effects of Calcium Hydroxide, Chlorhexidine and Mineral Trioxide Aggregate on the Viability of Candida albicans

Stavileci M*,Hoxha V,Bajrami D,Dragidella A

Objective: The aim of this study was to evaluate the effects of calcium hydroxide, chlorhexidine, and mineral trioxide aggregate (MTA) on the viability of Candida albicans.
Method: Sabouraud Dextrose Agar plates were prepared that contained different concentrations of calcium hydroxide, chlorhexidine, or MTA powder. The plates were inoculated with an overnight culture of C. albicans, and the presence of colonies that formed were observed after incubation at 37°C for 1, 24, 48, and 72 hours.
Results: Chlorhexidine and MTA, but not calcium hydroxide, inhibited colony formation. The minimum inhibitory concentration of MTA and chlorhexidine against C. albicans was 50 mg/ml.
Conclusions: We found that MTA and chlorhexidine inhibited the growth in agar of C. albicans within three days.