热带病与公共卫生杂志

抽象的

Assessment of WHO hemoglobin color scale for accuracy in diagnosis of anemia among pregnant women by health care providers in peri-urban settings in Karachi

Adeel Ahmed Khan

Diagnosis of anemia is commonly based on clinical examination which shows variable results. A non-invasive, low cost technique, WHO Hemoglobin Color Scale (HCS), could be utilized in primary health care settings to enhance the detection of anemia among pregnant women. The objective of our study was to measure the diagnostic accuracy of HCS and clinical signs assessment technique (CSAT) in diagnosing anemia against the gold standard of Laboratory Hemoglobinometry. We conducted a cross sectional validation survey comprising of 189 pregnant women from peri-urban settings in Karachi. Two maternal and child health centers (MNCH) from four towns (Gadap, Kemari, Bin Qasim and New Karachi) were included as study sites. Anemia was assessed by HCS method & CSAT, and compared with gold standard of laboratory hemoglobinometry. Around 72.7% women were diagnosed anemic by gold standard method. The sensitivity and specificity of HCS was 70.9% and 49.06% respectively while for CSAT: 95.7% and 5.66%. The positive (PPV) and negative (NPV) predictive values of HCS were 78.7% and 38.8% respectively while for CSAT: 72.9% and 33.33%. ROC curve analysis also showed the diagnostic accuracy of HCS method was better than CSAT (p< 0.05). The scope of HCS in diagnosing anemia seems to be limited but found to be better than clinical examination. Further research may be done to assess combinations of both parameters to optimize anemia diagnosis in resource poor settings.