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Asymptomatic Bacteriuria in Elderly Patients with Diabetes Attending a Tertiary Care Center

Manish Rijal, Biswas Neupane, Prabin Bhandari and Sagar Aryal

Introduction: A symptomatic bacteriuria (ASB) is the presence of at least 105 colony-forming units (CFU) per ml of 1 or 2 bacterial species in clean-voided midstream urine sample from an individual without symptoms of urinary tract infection (UTI). The objective of this study was to determine the prevalence of asymptomatic bacteriuria in diabetic patients and also to establish the antimicrobial susceptibility pattern of the pathogens. Methodology: Urine sample was collected from above 30 years old diabetic patients who attended Diabetes Endocrinology and Thyroid Care Center, Lalitpur for regular blood sugar estimation between the periods of August 2012 to April 2013. Culture and Antibiotic susceptibility test were performed using standard microbiological technique. Results: A total 18.4% out of 467 diabetic patients had ASB. Escherichia coli (47.7%) were the most predominant organism followed by Klebsiella pneumoniae. Imipenem (100%), nitrofurantoin (96%) and amikacin (87%) were found to be the most sensitive antibiotics against the urinary isolates. Conclusion: The prevalence of ASB is high in diabetic patients and poor glucose control can be considered a predisposing factor. Routine urine culture can be recommended for diabetic patients even when there is no urinary symptom.