生物等效性和生物利用度杂志

抽象的

Bioequivalence, Interchangeability and substitution

David Sebastian

Makers should lead studies to decide if their form is bioequivalent to the first medication—that will be, that the conventional rendition delivers its dynamic fixing (the medication) into the circulation system at for all intents and purposes a similar speed and in basically similar sums as the first medication.Since the dynamic fixing in the nonexclusive medication has effectively been appeared in testing of the brand-name medication to be protected and powerful, bioequivalence concentrates just need to show that the conventional adaptation delivers practically similar degrees of medication in the blood over the long run and subsequently require just a moderately modest number (24 to 36) of solid volunteers.