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Biogenic Synthesis of Silver Nanoparticles and Valuation of their Antimicrobial Activity against Dengue Larvae

Naz S, Nawaz H, Arshad U, Ansari F, Shahzadi R, Anjum FR and Bashir F

Dengue is a viral illness that is spread by a female mosquito Aedes aegypti. The occurrence of dengue has increased about 30 times. Half of the world’s population is endangered by this disease as statistics provide a data of 50-million cases reported annually, while currently the disease is endemic in more than 100 countries. It can be controlled by number of ways but most preferred and environmental friendly method is biological control. For this purpose, Silver nanoparticles were successfully synthesizing by using Bacillus thuringiensis. The Surface Plasmon Resonance (SPR) property of synthesized nanoparticle was studied by UV-Vis spectroscopy and the peak of the spectra was found to be at 420 nm. The XRD study gives results that the nanoparticle form in the process is crystalline in nature. The larvicidal activity of silver nanoparticles concludes that the silver nanoparticles show significant larvicidal activity against Dengue vector A. aegypti. The biosafety analysis proved Bt-AgNPs safe for other biological species.