干细胞研究与治疗杂志

抽象的

Can Umblical Cord-Derived Mesenchymal Stem Cells be used in Retinal Diseases: A Case Presentation of Leber Congenital Amaurosis

Ayse Oner*, Neslihan Sinim Kahraman

Human umblical cord blood is an excellent source of stem and progenitor cells which increase secretion of neurotrophic factors. These cells are known to have neuroprotective effect in neurodegenerative processes. The numbers of clinical reports including implantation of stem cells in retinal diseases are increasing rapidly. This paper aimed to review the safety and efficacy of umblical cord derived mesenschymal stem cell implantation in retinal pathologies. We also present the first clinical case of a hereditary retinal disease called Lebers' congenital amaurosis with the sixth month follow-up results after stem cell treatment.