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Chitosan Nanoparticles And Functional Repair Of CNS Tissue
Jun Lu
Maintaining the physiological structure and function of a cell necessitates maintaining the integrity of the cell membrane. After cell membrane disruption, for instance, immediate function loss, progressive degeneration, and the death of neurons following acute spinal cord injury (SCI). After damage, spontaneous membrane self-repair is frequently initiated, but it fails to overcome the overwhelming tissue distortion and physiological disturbance, such as unregulated Ca2+ influx, the generation of reactive oxygen species (ROS), and subsequent lipid peroxidation (LPO). In the early stages of Central Nervous System (CNS) damage interfering with progressive secondary injury; it would be most important of all therapies to restore membrane integrity quickly and effectively.