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Efficacy, Human Safety and Collateral Benefits of Alphacypermethrin Treated Long-Lasting Insecticidal Net (Interceptor®) in a Hyperendemic Tribal Area of Orissa, India

Surya K. Sharma, Prajesh K. Tyagi, Ashok K. Upadhyay, Mohammed A. Haque and Om P. Agrawal

Interceptor net® is a long-lasting insecticidal net (LN) made of multifilament polyester fabric in which the insecticide alphacypermethrin is incorporated directly into the polymers at a dose of 200 mg/m2. This paper presents the results of an efficacy trial on Interceptor nets on malaria transmission in an area under the influence of pyrethroid susceptible vector species Anopheles culicifacies and A. fluviatilis in Sundargarh District, Orissa, India. There was a reduction of 57-76% in malaria incidence in Interceptor net area as compared to the control areas. Cross-sectional point prevalence surveys showed a reduction of 73.1% and 40% in malaria prevalence in Interceptor net and untreated net users respectively, whereas there was an increase of 17% in no net villages. The net usage rate in the study population was between 80-98% during different months. With respect to the adverse effects of the insecticide, people reported skin irritations but transitory in nature hence did not pose any danger. Interceptor nets also provided collateral benefits in terms of relief from other household pests such as head lice, bed bugs, cockroaches, ants and houseflies.

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