全球生物学、农业与健康科学杂志

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Efficacy of Herbal Control of the Yeasts Isolated from Autistic Children

Wagih A. El-Shouny, Samira Ismail, Nessma Elzawawy,Samah Hegazy

Autistic children were reported to have gastrointestinal problems more frequent and severe than in normal children. The observation that antifungal medications improve autism behavior, made us aims to investigate their intestinal colonization with yeasts, the risk of yeast overgrowth in autistic behavior and evaluation of the antifungal activity of some plant extracts and essential oils on yeasts isolated from autistic children in vitro, 25 cases diagnosed as autistic children were taken as test group and 10 normal children were considered as a control group. Isolated yeasts from autistic children were identified and tested to be inhibited growth by some essential oils and plant extracts through agar well diffusion method. Minimum inhibitory concentration was determined to the clove extract. This study indicated that heavy growth of yeasts in stool culture among autistic children is common features without considering level of autism severity; Clove oil and extract have considerable antifungal activity against isolated yeasts.