临床与实验药理学杂志

抽象的

Global Tests Evaluating the Functional Condition of Hemostasis

Solovyev MA*,Tutrin II,Udut VV,Borodulina EV,Turenko AV

Abstract Control of effectiveness of global tests evaluation of the functional state regulation of blood aggregation provided an opportunity to obtain timely information about the I-II and III phases of hemostasis while using native substrate - whole blood. Ex vivo, registered during hemocoagulation of changing the viscous characteristics of whole blood, allowed to formulate the concept of fibrinogenesis permanence as in vivo existing process, defining proper hemostatic potential – integrative characteristic of the entire cycle of hemocoagulation, ensuring necessary blood fluidity and restricting extravasation of its components in case of defecting its permeability or damaging its vascular wall.