脑部疾病与治疗

抽象的

Impact of Deep Brain Stimulation Therapy on Autonomic Disturbances and Related Symptoms of Parkinson's Disease

Xiang Hong Wang, Laura Sperry1, John Olichney,Sarah Tomaszewski Farias, Kiarash Shahlaie, Norika Malhado-Chang1, Vicki Wheelock1 and Lin Zhang1

Deep brain stimulation (DBS) is an effective treatment option for patients with Parkinson’s disease (PD), essential tremor and certain types of dystonia. DBS surgery is typically offered to patients that have diminishing benefits from dopamine replacement therapy with prominent motor fluctuations. Recent research has also shown that DBS can have a significant impact on non-motor symptoms (NMSs), including influencing autonomic and related symptoms. In this editorial, we will evaluate these publications and discuss the often positive impact of DBS on autonomic symptoms, weight changes, sleep disturbances and sensory function.