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Impact of Insulin on Memory Recall

Yuki Totani, Junko Nakai, Etsuro Ito

Recent studies revealed that an injection of insulin into the central nervous system ameliorates deficits in memory formation and recall in snails. A spontaneous increase in the insulin levels in snails is also associated with improved memory recall. Thus, insulin is thought to be a critical factor for memory recall in snails. In the present study, we describe the production and function of insulin in the snail central nervous system for memory recall and expand this scenario to other animals. These findings provide a new avenue for studying the mechanisms underlying learning and memory.