干细胞研究与治疗杂志

抽象的

Induced Pluripotent Stem Cells and Their Future Therapeutic Applications in Hematology

Khalid Ahmed Al-Anazi

Induced pluripotent stem cells have recently acquired particular attention because of the following reasons: they can be derived from a wide variety of cells and tissues, their use can avoid many of the obstacles and ethical issues that limit the use of other stem cell lines and their rapidly advancing therapeutic and clinical applications. These cells can be efficiently utilized in regenerative medicine, tissue engineering, disease modeling, drug development and discovery, genetic therapies as well as various types of cell treatments.
Plenty of human and animal studies have already shown that these cells have great potentials for treating benign as well as malignant hematological disorders and that they can be utilized to generate several blood cell lines which may be used in clinical practice. In this review, several aspects of induced pluripotent stem cells will be discussed with the main focus on their future clinical applications in the field of hematology.