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Jacob's Disease: A Case Report and Literature Review

Daniel Fernando Roscher*, Alberto Attaguile, Javier Benitez and Graciela Giannunzio

Although osteochondroma is the most common benign tumor of bone in the axial skeleton, it rarely involves the maxillofacial region. In the latter case, it mainly affects the mandible, particularly the condyle. Very occasionally, it may affect the coronoid process and lead to the formation of a pseudo joint with the zygoma, a condition termed Jacob’s disease. This results in restricted mandibular movement and often causes midfacial asymmetry. We herein report the case of an 18 year-old female patient with a history of limited mouth opening for several years. Computed tomography and 3D reconstruction showed an exophytic tumor in the coronoid process, and a close relationship between the coronoid process and the malar and zygomatic arch. Total resection of the tumor and coronoid process was performed. The histopathological diagnosis was osteochondroma, confirming diagnosis of Jacob’s disease.