疼痛管理与医学杂志

抽象的

Low Dose Cannabidiol for the Treatment of Mild to Moderate Musculoskeletal Pain

Debra Kimless, Matthew K Caloura*, Susan Lewis, Stephen Goldner

Sixteen healthy, cannabis and cannabidiol (CBD) naïve patients with mild to moderate musculoskeletal pain took a single dose of 5 mg CBD sublingual tablet. Patients were using other-the-counter (OTC) medications to treat various manifestations of musculoskeletal pain, including neck, back, muscle aches, and arthritis. The average self-reported pain scale score (NPRS), measured on a scale of 0-10, was 5.13 prior to taking the CBD tablet. After tablet administration, the patients self-reported their pain scale score over a 2-hour period. All patients reported pain reduction within 20 minutes after taking the tablet and continued over the 2-hour period where the average reported pain was reduced by 20-fold (NPRS 5.13 to 0.25) and was statistically significant (p<0.001). No patients reported any adverse effects and characterized the experience as positive. The results of this study suggest that low dose CBD is an effective option for the treatment of mild to moderate musculoskeletal pain.