药物警戒杂志

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Non-Fatal Thrombin Based Hemostatic Matrix Pulmonary Embolism in Laparoscopic Surgery. A Case Report

Mura P, Fakir S, Mura S, Onida P and Finco G

Locally applied hemostatic agents, are used in various surgical procedures. In our case a thrombin based hemostatic matrix (FloSealTM) was used in the hepatic bed to facilitate haemostasis in a 63 year old-male undergoing video-laparoscopic cholecystectomy. Immediately after the surgery the patient developed severe anxiety, acute shortness of breath with associated hypoxia. An angiographic computerized tomography chest scan demonstrated multiple bilateral sub segmental pulmonary emboli that resolved in the following 12 h. A bilateral lower extremity duplex ultrasound showed no evidence of deep venous thrombosis.