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Post Intra-Alveolar Extraction Analgesia of Bupivacaine and Lidocaine: A Randomized Controlled Clinical Trial

Emmanuel A A, Olatokunbo BA and Olalere OG

Background and Aim: Pain is a common complaint following exodontia which usually occurs in the first six to twelve hours post-extraction.

Objective: The aim of this study was to evaluate the post-extraction pain control of 0.5% Bupivacaine compared with 2% Lidocaine following intra-alveolar tooth extraction.

Materials and Methods: This study was a double blind randomized controlled trial on patients who underwent intra-alveolar tooth extraction. There were two groups of 126 subjects per Bupivacaine and Lidocaine group respectively. Pain experience was assessed using Numeric Rating Scale (NRS). Data were analyzed using SPSS and P<0.05 was considered statistically significant.

Results: Post-operative pain was recorded in Lidocaine group between 3 to 12 hours post-extraction with significant improvements afterward while in the Bupivacaine group, there was almost pain-free period for the first 8 to 9 hours postoperatively. A significant reduction in the need for post-operative analgesics was noted in the Bupivacaine group. Overall patient satisfaction was significantly higher for the Bupivacaine group.

Conclusion: Bupivacaine appears to offer more effective post-operative pain control following intra-alveolar tooth extraction.