热带病与公共卫生杂志

抽象的

Pulmonary Haemorrhage due to Hump-Nosed Viper Bite: Excellent Response to Methyl Prednisolone-Case Report and Review of Literature

Arthihai Srirangan, Jagath Pushpakumara and Kamani Wanigasuriya

Background: Hump-nosed viper bite, the commonest venomous snake bite in Sri Lanka, is associated with significant morbidity. Specific anti-venom is not available for hump-nosed viper envenomation which is usually managed with supportive treatment. Pulmonary hemorrhage is an unusual manifestation of hump-nosed viper bite. Here we present a case of hump-nosed viper envenomation which complicated by pulmonary hemorrhage and was successfully treated with systemic steroids. To the best of our knowledge, it has not been reported in the literature before.

Case Presentation: A previously healthy 55-year-old man presented to the local hospital 18 hours after a humpnosed viper bite. He developed bilateral severe pulmonary hemorrhages, evidenced by rapid desaturation which needed intubation and mechanical ventilation, bleeding from the endotracheal tube and bilateral alveolar shadows in a chest X-ray. He had no other bleeding manifestations. Because of the life-threatening situation, he was treated with methylprednisolone pulse therapy. There was a rapid improvement of hypoxia with a resolution of X-ray changes. He was successfully weaned off from the ventilation after 24 hours.

Conclusion: This case highlights the importance of suspecting pulmonary hemorrhage in a patient who develops desaturation and alveolar shadow following hump-nosed viper bite even in the absence of other bleeding manifestation. Early and timely treatment with systemic steroid can be lifesaving in such patients.