Youjun Feng, Huimin Zhang, Min Cao and Changjun Wang
Streptococcus suis (S. suis) comprising thirty-five different serotypes, constitute a group of complex bacterial species that not only is swine pathogen, but also cause opportunistic infections in humans. A collection of virulence determinants have been largely elucidated that contribute to better understanding of pathogenesis underlying severe infections by S. suis. Here, we concentrated on control of S. suis virulence by a rainbow coalition of regulators, and discussed future perspectives in this field. It might provide a glimpse of the complex network of virulence regulation in S. suis.