Revisited Role of B Cells in Atherosclerosis

Paula Blair and Pasquale Maffia

B cells play a crucial role in both humoral and adaptive immune responses and are detectable in murine and human atherosclerotic arteries. Recent findings from mouse models are starting to re-define the complex role(s) of B-cells in the atherosclerosis. We will discuss the involvement of different B-cell subsets in vascular pathology and how B cells could be targeted for therapeutic utility.