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Risk of cardiovascular complications in idiopathic nephrotic syndrome

Evisina Hanafiati Frans

Risk of cardiovascular complications exists in patients with Idiopathic Nephrotic Syndrome (INS). These patients frequently have several risk factors, such as types of INS, hypertension, obesity, nephrotic dyslipidemia, long term treatment with steroids.

The aim of this study was to evaluate the cardiovascular complications and its relation to different types of INS.

All INS children in Pediatric Nephrology Outpatient Clinic of dr. Soetomo Hospital, Surabaya were included in this cross-sectional study between April and June 2016. They were three groups, group 1 Frequent Relaps NS (FRNS), Steroid Dependent NS (SDNS), and Steroid Resistant NS (SRNS). The medical records of each patient were reviewed for the following information: age, gender, and age at diagnosis, treatment of steroid, BMI, and blood pressure. Blood samples were collected to determine routine biochemical parameters. Echocardiography was performed to measure Left Ventricular End Diastolic Dimension (LVEDD), Left Ventricular Mass (LVM), and Ejection fraction (EF). Statistical analysis using Spearman correlation test.