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Safety of the COVID 19 Vaccines: Implications for Future Vaccine Development

Hazique P Koul, Parvaiz A Koul

The past few years have witnessed development of new vaccines especially for highly pathogenic viruses like the SARS CoV2 and Ebola. Rollout of the vaccines against SARS CoV2 was the fastest ever recorded in the history of modern medicine and it was indeed a creditable feat achieved by the basic scientists and manufacturers to develop and actually administer a vaccine within months of the detection of a virus. These developments have been made possible and informed by advances in basic biology and vaccine science, including new vaccine antigens, newer and advanced vaccine platforms and newer vaccine adjuvants. While the EUA (emergency use authorization) for the developed vaccines by authorization agencies listed them as safe and effective but questions have been raised about the extent the safety of these vaccines, given their speedy development and a perceived ‘less than optimal’ time for long term safety.