心血管药理学：开放获取

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Spontaneous Coronary Artery Disease: A life threatening condition in young women - Data from a public sector Hospital of Pakistan

Khalida soomro

Spontaneous coronary artery dissection is   important cause of ACS in young women, responsible for up to 25% of all ACS cases in women <50 years of age. The common predisposing factors for SCADare  postpartum, fibromuscular dysplasia , connective tissue disease and hormonal therapy in women,swho are  thought to have more fragile coronaries usually. Spontaneousruptureis aggravated by various  triggers  increasing   shear stress on coronary arteries  leading to commonlyST-elevation MIin up to 50% of patients and with non-ST-elevation MI in the rest. Patients may present with early  complication like  Life-threatening ventricular arrhythmias and sudden cardiac death..

PCI is the preferred revascularisation strategyand has reported success rate of <50% in developed countries CABG can be considered for  left main stem dissections or when PCI has been unsuccessful or is not technically feasible . we are presenting the data  of study conducted in Cardiology department of Dow university of health and Sciences at Karachi Pakistan during the  years 2013 to 2016suggest  that 22% young women had SCAD and 13 to 17 %had PCi failure and needed emergency CABG where as only   6% cases under went emergency CABG . every PCI center of cardiology set updoesn’t have the surgical back up in Pakistan ,

So the purpose of this presentation is to present data  ofthe resource constrained cath labs with poor surgical back up in 24hrs. its impact on the mortality and morbidity of women patients