脑部疾病与治疗

抽象的

Sudden Unexpected Death in Parkinson’s Disease and the Pharmacological Modulation of the Ca2+/cAMP Signaling Interaction: A Shot of Good News

Afonso Caricati-Neto1, Fúlvio Alexandre Scorza2 ,Carla Alessandra Scorza2, Roberta Monterazzo Cysneiros3, Francisco Sandro Menezes- Rodrigues1, and Leandro Bueno Bergantin1*

This discusses how pharmacological modulation of the Ca2+/cAMP signaling interaction could be an important neuroprotective and cardioprotective strategy to protect the dopaminergic neurons from cell death related to Parkinson’s disease (PD) and at the same time to prevent the cardiac collapse in sudden unexpected death in PD.