外科与麻醉杂志

抽象的

The Comparison Effect of Dexamethasone Single vs. Triple-Doses in Rhinoplasty-Induced Complications

Aliasghar Darzi

Introduction: Postoperative edema and ecchymosis may affect the patient and surgeon’s satisfaction from the result of cosmetic surgery. Corticosteroids have been used to reduce the rhinoplasty-induced complications. The aim of this study was to compare the efficacy of single versus three-doses of dexamethasone in postoperative complications following rhinoplasty.

Materials and Methods: This clinical study was performed on 100 patients who referred for rhinoplasty to Mehregan Hospital in Babol (located in Northern Iran). The patients were randomly divided into two groups: The first group received single dose dexamethasone and the second group received the same dose of dexamethasone before operation and the second and third doses 16 hours after that. The efficacy in these two groups reducing edema, ecchymosis and intraoperative bleeding were compared. 

Results: All patients (40% males, aged 23.95 ± 6.52 and 60% females, aged 25.26 ± 6.95) underwent open rhinoplasty with osteotomies. The degree of edema and ecchymosis observed were more than the group that received three doses of dexamethasone (p< 0.001).

Conclusions: Three-dose dexamethasone is more effective than single-dose dexamethasone administration in reducing edema, ecchymosis and intraoperative bleeding following rhinoplasty.