Tobacco role in the etiology of precancerous lesions

Adrian Creanga

The use of tobacco and tobacco smokeless has increased and has been associated with oral leukoplakia and other precancerous oral lesions. The presence of leukoplakia in adolescent users of smokeless tobacco is related to years of use, frequency of use, and amount used. Malignant transformation may occur in 0,5% to 6,2% of individuals and is expected to increase with years of use.

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