生物等效性和生物利用度杂志

抽象的

Transdermal Application of Drugs and Techniques Affecting Skin Barrier

Josef Jampilek

The development in the field of pharmaceutical dosage forms results in discovery of additional highly sophisticated drug delivery systems that allow maintaining constant level of active substance in organism. Transdermal administration of drugs represents an excellent alternative to conventional pharmaceutical dosage forms. However, transdermal drug delivery often faces the problem of insufficient or no penetration of active pharmaceutical substances through the skin.