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Wonder drug - an insect and fungus relationship (Hepialus - Cordyceps) through biotechnological approaches

*Siddique SS, Arif M, Babu R, Shamim M

Yartsa gumba or dbyar-rtswa-dgun-bu is Tibetan name of an entomo-fungal combination between Hepialus armoricanus (Lepidoptera; Hepialidae) larva and its parasitizing fungus Cordyceps sinensis (Berk), which is traditionally used in Tibetan and Chinese System of Medicine (TCM). This medicinal entomo-fungal product is known in Chinese as Dong Chong Xia Cao (winter worm and summer plant or grass in summer and worm in winter), Yarchagumba means herbs of life in Nepal and Tochukaso in Japan. It is also known as Caterpillar mushroom and Caterpillar fungus, and in India it is commonly known as Keera Ghas. This entomo-fungal combination is known to be used for many centuries as tonic, medicine and aphrodisiac and in religious ceremonies in China, Indonesia and Upper Himalayas. Yarsa gumba is also known as the “Himalayan Viagra” or “Himalayan Gold” for its high medicinal and commercial value. It is mainly used as a treatment for impotency in many countries. Numerous scientific studies reveal that it has properties of antibiotic in it. Cordycep sinensis is used for lung and respiratory infection, pain, sciatica and backache. It also provides vitality and increases physical stamina of the body. Yarsa gumba is used by the Chinese to cure chronic hepatitis B and immune function disorder such as dysfunctioning of liver. Approximately 5 grams was stuffed into the stomach of a duck that was roasted until well cooked, then the Cordyceps was removed and the duck was slowly eaten, twice daily, over a period of 8-10 days.